Exacerbation prediction and aerosol emissions

Investigating the impact of aerosol emissions on patients with COPD and asthma.

Theme Respiratory disease

This workstream has two parts. The first focuses on aerosol emissions. Aerosol emissions are particles people breathe out when talking, breathing, sneezing or coughing. Our work will look at the aerosols that people with lung disease create in various environments. This will help us understand the risk of airborne infections such as COVID-19 better.

Second, we will gather mobile app data from patients with chronic obstructive pulmonary disease (COPD) and asthma. We will use this data to see if we can predict when these patients may have a lung attack or ‘exacerbation’. Our aim is to help them avoid being admitted into hospital.

This work is especially important within population groups that are disproportionately affected by these diseases. To achieve this, we’re working with engineers, technology partners and other respiratory BRC themes in the UK, with access to different populations.

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AERATOR collaboration

Our AERATOR collaboration with the Bristol Aerosol Research Centre (BARC) pioneered the translation of aerosol…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Sensing, Prediction and Alerts in COPD Exacerbations (SPACE) Study I

We have previously looked at how patients with chronic obstructive pulmonary disease (COPD) use the…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Radiological assessment of pneumothorax

A pneumothorax is also known as a collapsed lung. It happens when air leaks into…

Theme Respiratory disease

Workstream Personalised care in pleural disease

Using circulating tumour DNA to diagnose pleural mesothelioma

As a tumour or cancer grows, its cells die and are replaced by new ones.

Theme Respiratory disease

Workstream Personalised care in pleural disease

Investigating the link between asthma and mental health in children

Asthma is the most common long-term condition among children and young people in the UK,…

Themes Mental health Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Investigating the link between asthma, brain inflammation and MRI changes

Eight million people in the UK have been diagnosed with asthma. Asthma + Lung UK…

Themes Mental health Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Exploring impact of mepolizumab treatment for asthma on brain structures and wellbeing

Patients with severe asthma are often affected by anxiety, depression and other conditions that influence…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Exploring the clinical and health economic impact of the myCOPD app

The aim of this project is to explore the health economic benefits of an app…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Sensing, Prediction, and Alerts in COPD Exacerbations (SPACE) Study III

The aim of this project is to continue developing digital tools that help us predict…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Saliva biomarkers in chronic obstructive pulmonary disease exacerbation

This project aims to validate a new point-of-care technology designed to look for certain biomarkers…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Sensing, Prediction and Alerts in COPD Exacerbations (SPACE) Study II

The Sensing, Prediction and Alerts in COPD Exacerbations (SPACE) studies aim to develop a…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Looking at long-term pleural disease outcomes: The SPOTLight study

The space around the lungs (the pleural cavity) can be affected by many different…

Theme Respiratory disease

Workstream Personalised care in pleural disease

Can suPAR be used as a biomarker for predicting complications in malignant pleural effusions? A pilot study

Pleural effusion, where fluid builds up in the space around the lungs (the pleural…

Theme Respiratory disease

Workstream Personalised care in pleural disease

BREATHE study

The BREATHE study (Bristol evaluation of novel a…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions