Research projects

Our projects span early stage studies such as first in human and feasibility studies to developing new research methodologies and tools. Take a look at all our projects across all our research themes and workstreams.

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Linking imaging and clinical data to improve orthopaedic surgery

Orthopaedic surgery often changes how a joint moves, sometimes in ways that are intended…
  • Theme Translational data science
  • Workstream Clinical informatics platforms

Can pleural fluid cell differentiation accurately diagnose the cause of fluid around the lung?

Pleural effusion – a build-up of fluid around the lungs – can be caused by…
  • Theme Respiratory disease
  • Workstream Airways diseases

Establishing a framework for trusted data sharing between ALSPAC and the South West SDE

The Avon Longitudinal Study of Parents and Children (ALSPAC) has followed around 30,000 participants…
  • Themes Mental health Translational data science
  • Workstream Clinical informatics platforms

Mental health support for patients with prosthetic joint infection and their families

Deep prosthetic joint infection is a devastating condition that can cause pain, disability and death.
  • Theme Surgical and orthopaedic innovation
  • Workstream Interventions to improve patient outcomes after surgery

Using pain science education to help patients having total knee replacement surgery

About 1 in 5 patients who have a total knee replacement have chronic pain after…
  • Theme Surgical and orthopaedic innovation
  • Workstream Interventions to improve patient outcomes after surgery

Developing care for patients with dislocation after total hip replacement

Hip replacement is a common operation. It’s performed to relieve pain and improve function. Eighty…
  • Theme Surgical and orthopaedic innovation

Can a target trial estimate the side effects of antidepressants in autistic adults?

Many autistic people experience poor mental health. The results of past research into treatments for…
  • Theme Mental health
  • Workstream Biological interventions, trial recruitment and safety

Play in urban spaces for health (PUSH)

Playing outdoors is a good way for children to get physically active. It helps their…
  • Theme Diet and physical activity
  • Workstream Population diet and physical activity

Reducing bias in research: Building better tools to combine study results

When researchers want to know whether something causes a health outcome, like whether a vitamin…
  • Theme Translational data science
  • Workstream Large, complex datasets