Research projects

Our projects span early stage studies such as first in human and feasibility studies to developing new research methodologies and tools. Take a look at all our projects across all our research themes and workstreams.

Exploring drug targets to treat and prevent cancer

It’s possible that some medications used for lowering blood sugar, preventing inflammation or supporting weight…

Theme Diet and physical activity

Workstream Clinical diet and physical activity

Investigating the link between asthma, brain inflammation and MRI changes

Eight million people in the UK have been diagnosed with asthma. Asthma + Lung UK…

Themes Mental health Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Mapping health services available to patients waiting for joint replacement

As of April 2023, over 40 per cent of people on NHS waiting lists (a…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Exploring how obesity influences cancer survival

Evidence from different studies suggests that obesity or body mass index (BMI) might play a…

Theme Translational data science

Workstream Genetic evidence to prioritise intervention

Supporting exercise before joint replacement

People waiting for a joint replacement often avoid physical activity as they believe it will…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Is hydrogel safe and effective for weight loss?

Surgery is the most effective but also the most expensive way for maintaining long-term weight-loss…

Theme Diet and physical activity

Workstream Clinical diet and physical activity

Exploring impact of mepolizumab treatment for asthma on brain structures and wellbeing

Patients with severe asthma are often affected by anxiety, depression and other conditions that influence…

Theme Respiratory disease

Workstream Exacerbation prediction and aerosol emissions

Using biomarkers and machine learning to predict antidepressant resistance

Around half of patients with depression don’t improve after taking antidepressants. Clinicians need to…

Theme Translational data science

Workstream Omics for prediction and prognosis

Can DNA methylation biomarkers predict whether pleural effusion is caused by cancer?

Pleural effusion, where fluid builds up in the cavity around the lungs, can develop…

Theme Translational data science

Workstream Omics for prediction and prognosis