Innovative translational research methods
Creating patient-centred, transparent systems for surgical innovation.
Translational research is research aimed at translating the results of research into something that benefits humans directly. This workstream focuses on creating patient-centred, transparent systems (or methodologies) for surgical innovation.
Our research has previously identified that current systems for surgical innovation are inadequate: understanding of adverse events is insufficient, patients aren’t given enough information, and sometimes their experiences are poor.
We are working with surgeon innovators to develop, pilot and refine our methodologies to create a safe, transparent, and comprehensive innovation life cycle.
Improving how we identify innovation and incremental modifications will improve informed consent. It will also reduce harm to patients, prevent the widespread use of innovation before it is evaluated and stop inappropriate use of harmful or ineffective practices.
Developing electronic methods for learning
As an individual surgeon gets experience of performing a procedure, they are likely to make…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Optimising how a first-in-human device for knee replacement is introduced
During knee replacement surgery, damaged sections of the knee are replaced with metal and plastic…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
The ALPACA study
High quality shared decision making processes that focus on the patient are an important part…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Developing protocols for managing digital videos of surgical procedures
There are many benefits to video recording surgical procedures. Recordings provide a lot of data…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Assessing minimally invasive surgery for oesophageal cancer
It is common for surgeons to modify new surgical procedures. Modifications don’t usually happen in…
- Theme Surgical and orthopaedic innovation
- Workstreams Innovative translational research methods Novel surgical and orthopaedic techniques and devices
Integrating care pathway components in surgical innovation research
Surgery is a complex healthcare intervention involving multiple interacting components. It is usually supported by…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Improving how surgical procedure modifications are reported
The way new surgical procedures are developed and evaluated is very different to how new…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Outcome assessment continuity in early and late phase surgical research
Early evaluation of innovative (new) surgical procedures and devices provides the evidence we need to…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Using AI to help with quality assurance in surgical studies
Surgery improves and saves millions of lives each year. Many operations are tested in randomised…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
A scoping review of equality, diversity and inclusion reporting in early-phase surgical research
Researchers often conduct early studies when new types of surgery are being developed. They test…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Improving how patients are selected for early evaluations of new surgical procedures and devices
Early evaluations are small studies about new or modified surgical procedures and devices. These studies…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Optimising the efficiency and value of burn care research
Burns affect 11 million people globally. They can lead to long-term disability and be associated…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
How do we stop or reduce treatments that don’t work or aren’t cost-effective?
Stopping or reducing how often a treatment is offered by the NHS is called ‘de-adoption’.
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Developing guidance for surrogate outcomes in clinical trials
SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) and CONSORT (Consolidated Standards Of Reporting Trials)…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Interviewing surgical teams to optimise new chemotherapy delivery method
Bowel, ovarian and stomach cancer often spreads (metastasises) to the lining (peritoneum) of the abdominal…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Improving methods for assessing surgical site infection
The aim of this project is to explore methods to improve surgical site infection (SSI)…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Understanding how new surgical procedures and devices are introduced
The overall aim of this study is to understand and improve how innovative surgical…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Quality of life in pressurised intraperitoneal aerosolised chemotherapy
This project aims to explore the views and experiences of patients with peritoneal metastases (cancer…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Comparing surgical procedures for gastro-oesophageal reflux disease
The aim of this project is to compare two types of surgical procedure performed by…
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods
Improving communication and innovation
National guidance states that patients must be fully informed if a treatment option is innovative.
- Theme Surgical and orthopaedic innovation
- Workstream Innovative translational research methods