Professor Golam Khandaker
Theme lead for Mental health
Workstream lead for Biological interventions, trial recruitment and safety
Golam Khandaker is Professor of Psychiatry, MRC Investigator, and Immunopsychiatry Programme Lead at the MRC Integrative Epidemiology Unit at the University of Bristol Medical School, and Honorary Consultant Psychiatrist at the Avon and Wiltshire Mental Health Partnership NHS Trust.
Prof Khandaker’s research focuses on identifying and validating novel immunological mechanisms and potential treatment targets for mental illness using epidemiological cohort studies, genetic analysis, and early phase clinical trials of anti-inflammatory drugs in patients with depression and psychosis.
Identifying biomarkers for treatment response and disease prognosis in depression
Chronic inflammation alters how the brain works, contributing to depression, cognitive decline, and other mental…
- Theme Mental health
- Workstream Biological interventions, trial recruitment and safety
Exploring associations between asthma and mental health disorders
Asthma is a very common lung condition. In the UK, 7.2 million people have asthma.
- Themes Mental health Respiratory disease
- Workstream Airways diseases
Exploring inflammation as a driver for post-operative complications
One in seven patients develop a serious medical problem after surgery. These types of complications…
- Theme Translational data science
- Workstream Omics for prediction and prognosis
Can we improve autistic people’s health by changing the medicines we prescribe?
Autistic people often have more health problems and a shorter life expectancy than non-autistic people.
- Theme Mental health
- Workstream Biological interventions, trial recruitment and safety
Predicting the risk of young people developing anxiety and depression
The number of adolescents experiencing anxiety and depression is increasing. We need to find better…
- Theme Mental health
- Workstream Biological interventions, trial recruitment and safety
Can a target trial estimate the side effects of antidepressants in autistic adults?
Many autistic people experience poor mental health. The results of past research into treatments for…
- Theme Mental health
- Workstream Biological interventions, trial recruitment and safety
Treatment resistance and drug side effects in schizophrenia
Schizophrenia is a mental health condition where people may see, hear or believe things that…
- Theme Translational data science
- Workstream Genetic evidence to prioritise intervention
Uncovering the biological links between e-cigarette use and mental health
E-cigarette use has become increasingly common, especially among young people, but its impact on mental…
- Theme Mental health
- Workstream Biological interventions, trial recruitment and safety
Investigating the link between asthma and mental health in children
Asthma is the most common long-term condition among children and young people in the UK,…
- Themes Mental health Respiratory disease
- Workstream Airways diseases
Investigating the link between asthma, brain inflammation and MRI changes
Eight million people in the UK have been diagnosed with asthma. Asthma + Lung UK…
- Themes Mental health Respiratory disease
- Workstream Airways diseases
Inflammation and mental health
In this blog post, originally written for and published by the MRC…
Pilot trial suggests anti-inflammatory drug could help difficult-to-treat depression
Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding…
Review finds lack of risk calculators to predict long-term depression and anxiety
There are very few risk calculators to predict how symptoms of anxiety and depression will…
Depression linked to immune response in some people
A link between depression and changes in counts of several types of immune cells in…