News
Accelerating precision orthopaedic surgery using automated imaging and linked clinical data
A new NIHR Bristol Biomedical Research Centre (BRC) research project to improve surgical planning and precision using automated image analysis plans to use the South West Secure Data Environment (SDE) to link clinical imaging with electronic patient records. The project is led by Mr Simon Abram. Linking…
Unpicking the genetics of postoperative delirium
The genetic variations that might make someone more likely to experience postoperative delirium are explored in a new Bristol Biomedical Research Centre (BRC) paper published in PLOS Medicine. Researchers from the BRC’s Translational Data Science Theme performed a genome-wide association study or GWAS. This type of study uses genetic…
Improving how missing data is handled in studies
A new tool to help statisticians decide how to handle missing data in studies has been published by Bristol Biomedical Research Centre (BRC) researchers. In health research, it’s common to have missing information in study data, especially in large studies about the risk factors for disease. This missing data can…
Understanding mental health care across the whole system through linked data
Mental health records from a major trust in the South West are to be linked to other datasets to unlock new research, thanks to a new project. It has historically been difficult to make use of routinely collected mental health for research. Data about mental health is amongst the most…
Booster jabs reduce the risks of COVID-19 deaths, study finds
Booster vaccines reduced the risk of COVID 19–related hospitalisation and death, according to a new study of over 3 million adults who had the autumn 2022 vaccine in England. The research, led by the universities of Bristol and Oxford, provides further evidence of the effectiveness of booster vaccination against COVID-19.
New project explores data sharing between Children of the 90s and South West SDE
A new project led by the National Institute for Health and Care Research Bristol Biomedical Research Centre (NIHR Bristol BRC) will explore how data from Children of the 90s can be made available through the South West Secure Data Environment (SDE). The project aims to establish a framework for trusted…
Researcher and GBBO finalist team up to explain Bristol BRC project in cake form
Bristol Biomedical Research Centre researcher Lavinia Paternoster has teamed up with Great British Bake Off 2023 finalist Josh Smalley to bring a research project to life through the medium of cake. The pair baked vanilla cupcakes with passionfruit curd to explain Lavinia’s Medical Research Foundation funded project…
Using genetic data to pinpoint the causes of medication side-effects
From weight-gain to low white blood cell count, side-effects are the main reason people stop taking antipsychotic medication. The biological mechanisms causing these side-effects have been revealed in a new, ground-breaking study. The research, published in PLOS Genetics, was led by University of…
Study reveals stark ethnic and social disparities in stillbirths within individual hospitals and healthcare trusts in England
Stillbirth rates are known to be higher for Black and Asian women than for white women, and those living in the most deprived areas are more at risk than those in the least deprived areas. Now a new University of Bristol-led study involving Bristol BRC researchers, published in the…