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Switching to non-surgical approach to ankle fractures in older people could save £1.5 million a year

  • 15 September 2020
If half of patients aged 60 and over who had surgery for an ankle fracture instead had a non-surgical treatment called close contact casting, the NHS could save around £1.5 million a year, according to a new analysis from researchers at NIHR Applied Collaboration West (ARC West) and the NIHR…

"Our patient advisory group has been invaluable"

  • 15 September 2020
The BRC’s Cardiovascular theme has been working with its patient advisory group (PAG) since 2017. Jade Salter-Hewitt, Senior Clinical Trials Research Administrator, shares how the group has evolved and the contribution it makes. Our group is made up of nine members, all of whom are either living with chronic heart…

Genetic study of proteins is a breakthrough in drug development for complex diseases

  • 8 September 2020
An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit (MRC-IEU) at the University of Bristol, has demonstrated how genetic data can be used to support drug target prioritisation by identifying the causal effects of proteins on diseases. Working in collaboration with…

NIHR Bristol BRC contributing to ground-breaking national study into long-term health impacts of coronavirus

  • 4 September 2020
A major UK research study into the long-term health impacts of COVID-19 on hospitalised patients has been launched. The PHOSP-COVID study has been awarded £8.4million jointly by UK Research and Innovation (UKRI) and the National Institute for Health Research (NIHR). This study is one of a number of COVID-19…

Analysis of seven trials finds that corticosteroids reduce risk of death by 20 per cent in critically ill COVID-19 patients

  • 2 September 2020
Corticosteroids reduce the risk of death among critically ill COVID-19 patients by 20 per cent, an analysis of seven trials published today [2 September] in the Journal of the American Medical Association (JAMA) has found. The results of three of the trials included in the meta-analysis are also published in…

Handgrip strength shown to identify people at high risk of type 2 diabetes

  • 2 September 2020
Findings demonstrate handgrip strength could be a cost-effective early screening tool A simple test such as the strength of your handgrip could be used as a quick, low-cost screening tool to help healthcare professionals identify patients at risk of type 2 diabetes. In new research, scientists at the universities of…

Implant choice more important than surgeon skill for hip replacement success

  • 31 August 2020
A study analysing over 650,000 hip replacement patients across England and Wales over 14 years sought to investigate why one hospital has consistently been identified as having better than expected outcomes compared to other settings. The findings have shown that the outstanding hip implant survival results seen in one centre…

Shoulder replacements benefit most patients for more than 10 years, study shows

  • 27 August 2020
More than 90 per cent of shoulder replacement implants last more than 10 years, according to the largest study of its kind. The study led by the University of Exeter and the National Institute for Health Research Applied Research Collaboration South West Peninsula (PenARC), and published in The…

Body mass index may not be the best indicator of our health – how can we improve it?

  • 30 July 2020
By Dr Karen Coulman, Research Fellow (NIHR Clinical Lectureship), and Dr Sarah Sauchelli Toran, Senior Research Associate, at the University of Bristol and the NIHR Bristol BRC Nutrition, Diet and Lifestyle theme. Their article was originally published in The Conversation, 29 July 2020. Body mass index or…