Cardiovascular disease

Increasing the chance of survival and reducing complications for patients undergoing cardiac surgery.

We develop interventions to prevent or treat complications in cardiac surgery patients of all ages. This includes severe bleeding, kidney damage and neurological complications as well as reducing the time they will have to spend in intensive care after surgery. We also engineer new types of vascular grafts with the ability to grow. This extends the lifespan of grafts, reducing the number of times a child may have to undergo heart surgery for correction of an inherited heart defect.


Minimising surgical bleeding

Feasibility studies for treatments and point of care testing

Avoiding acute kidney injury (AKI)

Predicting and treating post-operative kidney injury in adults and neonates

Avoiding neurological complications

Identifying markers and evaluating interventions and protective devices

Avoiding prolonged ventilation

Investigating the role of stress hormones in the peri-operative period

Enhanced longevity of heart valves and vascular conduits

Using stem cells technology to develop the next generation of cardiac grafts and prostheses


Understanding and predicting complications of cardiac surgery

Using large-scale data to investigate whether metabolic and genetic factors can help predict cardiac surgery complications

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Academic Lead

ThemeĀ  Manager

Latest research news

“Our patient advisory group has been invaluable”

15 September 2020

The BRC’s Cardiovascular theme has been working with its patient advisory group (PAG) since 2017. ...

Understanding the deadly link between COVID-19 and cardiovascular disease

23 June 2020

Deborah Lawlor, Professor of Epidemiology at the University of Bristol and the NIHR Bristol BRC, ...