Improving outcomes for in vitro fertilisation (IVF)

Led by Deborah Lawlor

This workstream aims to improve IVF treatment strategies and establish a clinical group of IVF patients.

In vitro fertilisation (IVF) livebirth success is approximately 30% but varies by couple and treatment characteristics.

In our existing research we have developed a tool that accurately predicts live-birth rate in women receiving IVF. In addition, we have demonstrated the ideal number of embryos to transfer in IVF individualised to each woman and shown that with repeat cycles of IVF women can achieve live-birth rates similar to those with spontaneous conception (but take twice as long to achieve these rates). This work has influenced clinical practice through national and international guidelines.

Our aim in this work stream is to:

  • Complete new studies to improve emerging IVF treatment strategies, such as separating ovarian stimulation from embryo transfer (also known as ‘freeze-all’).
  • Establish a clinical cohort of IVF patients in order to understand the factors that influence IVF success. Find out more about the Bristol IVF Study.